Neurobiology

Curriculum guideline

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Course
BIOL 3621
Discontinued
No
Course code
BIOL 3621
Descriptive
Neurobiology
Department
Biology
Faculty
Science & Technology
Credits
4.00
Start date
End term
Not Specified
PLAR
No
Semester length
15
Max class size
35
Contact hours
4 hrs/week Lecture/Group discussion 2 hrs/week Laboratory
Method(s) of instruction
Lecture
Lab
Learning activities

There are four hours of classroom instruction (lecture, tutorials, group discussions) and two hours of laboratory instruction per week.

Course description
The course will provide an overview of neural cell biology, neurophysiology and neurochemistry. The molecular and cellular basis of the sensory and motor functions in animals, including their behaviour, will be examined. The theory component will be accompanied by case studies and discussions of current neuroscience topics.
Course content

1. Evolution of the Nervous Systems

  • Hypotheses on the evolutionary origin of neurons

  • Trends in the evolution of the invertebrate nervous system

  • Evolution of the vertebrate brain

  • Convergent evolution of intelligence

2. Neuroanatomy

  • General organization of the human nervous system

  • Functional anatomy of the brain and the spinal cord

  • Cellular neuroanatomy: neurons and neuroglia

  • Ventricles and meninges

  • Main tracts, nuclei, nerves and ganglia

  • Embryonic development of the nervous system

3. Brain Circulation and Metabolism

  • Blood supply to the central nervous system

  • Vascular territories of the cerebral arteries

  • Cerebral energy metabolism

  • Myelin formation and structure

  • Neurotransmitter synthesis

4. Neural Signalling

  • Ion channels and neuronal membrane potential

  • Local signalling: passive electrical properties of the neurons

  • Propagated signalling: the action potential

  • Synaptic transmission and synaptic integration

5. Sensory Pathways I

  • Coding of sensory information

  • The somatosensory system

  • The perception of touch, pain and temperature

6. Sensory Pathways II

  • Vision: retinal processing and visual pathways

  • Hearing: sensory transduction and auditory pathways

7. Motor Control I

  • Organization of the motor systems

  • Lower motor neuron circuits

  • Upper motor neuron circuits

  • Posture and locomotion

8. Motor Control II

  • Cerebellum

  • Basal ganglia

  • The control of gaze

9. Brain & Homeostasis

  • Spinal cord, brain stem and reflexive behaviour

  • Arousal and sleep

  • Hypothalamus

  • Autonomic nervous system

10. Brain & Behaviour

  • Functional organization of the cerebral cortex

  • Cellular mechanisms of learning and memory

  • The limbic system and emotions

11. Laboratory topics

  • Brain anatomy

  • Neuronal histology

  • Invertebrate behaviour

  • Invertebrate neuropharmacology

  • Neurophysiology through computer models

  • Neurophysiology through experiments with human subjects (with Ethics Approval)

Learning outcomes

Upon completion of this course, students will be able to:

  1.  Outline the main trends and milestones in the evolutionary history of the nervous system in invertebrates and vertebrates.

  2. Describe the structure and components of the human nervous system.

  3. Identify the unique biochemical, metabolic and physiological characteristics of the brain.

  4. Discuss the cellular and molecular processes involved in the generation, propagation and transmission of nerve impulses.

  5. Describe the neural pathways involved in the acquisition, conduction and processing of sensory information.

  6. Describe the neural pathways involved in the generation and control of movement.

  7. Discuss the mechanisms by which the autonomic nervous system contributes to homeostasis.

  8. Explain the neural basis of complex brain functions such as learning, memory and emotions.

  9. Discuss the application of various research methods to decipher the structure and function of the nervous system.

Means of assessment

Evaluation will be carried out in accordance with Douglas College policy. The instructor will present a written course outline with specific evaluation criteria at the beginning of the semester. Evaluation will be based on the following:

Evaluation Marks
Quizzes 15-20
Assignments & lab reports   5-10
Midterm examination 20-25
Term paper  10-15
Final examination 30-35
TOTAL 100
Textbook materials

Students should consult the Douglas College Bookstore for the latest required textbooks and materials.

Prerequisites

BIOL 2103

Corequisites

None

Equivalencies

None

Which prerequisite

None